To treat wounds and aging, a technique for human skin regeneration


 

Researchers have come up with a technology that will regenerate human skin, allowing it to repair itself like the characteristics of a newborn baby. In an exciting study on mice, a team of researchers from the University of Washington managed to identify a genetic factor in the skin of newborn mice that controls the formation of hair follicles as they grow during the first week of life.


The researchers found that a similar genetic factor in humans usually stops being active after the skin is formed in adult tissues, but they note that when this factor is activated in the relevant cells in adult mice, their skin was able to recover and heal wounds without scarring.


The researchers also noted that the skin, which regenerated and repaired in adult mice, contained fur, and could develop goosebumps, an ability that is missing in adult human scars.


In the research study, the team relied on the use of a new technique called single-cell RNA sequencing to compare genes and cells in developing and adult skin. They found that in developing skin, proteins that attach to DNA can influence or disable gene activity. They also found that a specific genetic factor was linked to the growth of the layer of skin just below the surface, which gives the skin its youthful, firm appearance.


When testing the capabilities of this genetic factor by activating it in the skin of adult mice, they noted its effectiveness in enhancing the skin's ability to regenerate and repair wounds, while reducing the occurrence of scars, and the growth of new active hair follicles was observed.


The results of the study are promising and exciting, as they highlight the possibility of improving the treatment of skin wounds, as well as avoiding some aging processes. The detection of this genetic factor and its link to skin regeneration is a first of its kind in the modern medical and research field.


Experts point out that the results so far open a new hope for making human skin regeneration a reality, as well as providing better possibilities for treating wounds and scars and addressing some problems associated with aging, such as premature skin aging while working on further research and studies in this regard.

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