A new study reveals that good quality sleep and avoiding sleep apnea can boost brain power

A new study has found that good quality sleep and the absence of sleep apnea are associated with better cognitive function in adults aged 58–89.

The study, published in JAMA Network Open, investigated 5,946 adults in the U.S. in five independent community-based cohorts involved in an overnight sleep study and neuropsychological assessments.

The researchers found that better sleep quality and the absence of sleep apnea were associated with better cognition over five years of follow-up. Individual differences in the composition of sleep, such as the time spent in light sleep, deep sleep, and REM sleep, were not associated with cognition.

"These findings suggest that in adults without dementia, sleep consolidation and the absence of sleep apnea may be particularly important for optimizing cognition with aging," the researchers wrote.

Lead author and Monash University Associate Professor Matthew Pase said the findings suggested that the role of interventions to improve sleep for maintaining cognitive function required investigation.

"At least half our sample had evidence of at least mild obstructive sleep apnea," he said.

"I think the most interesting finding is that participants that have mild to severe sleep apnea had worse cognition, so they had worse thinking and memory performance, for example.

"This is significant because there have been some studies that have shown relationships between obstructive sleep apnea and poor cognition, but they've genuinely relied on people with a diagnosis.

"The take home is that our findings suggest different elements of sleep are important for cognitive health, particularly the quality of someone's overnight sleep and whether or not they have sleep apnea."

The study is the first to come from the Sleep and Dementia Consortium, which was established to study associations between risk of dementia and markers of accelerated brain aging and injury measured with brain imaging and cognitive testing.

It is led by Associate Professor Pase and Associate Professor Jayandra Himali from the University of Texas in San Antonio.

The consortium curated gold standard data from five population-based cohorts across the U.S. with methodologically consistent, overnight, home-based sleep studies and neuropsychological assessments over five years of follow-up.

"This has allowed us to generate the best evidence yet as to which aspects of sleep are more important for cognitive health," Associate Professor Pase said.

The cohorts included the Atherosclerosis Risk in Communities study, Cardiovascular Health Study, Framingham Heart Study (FHS), Osteoporotic Fractures in Men Study, and Study of Osteoporotic Fractures.

Results were adjusted for demographic variables, the time between the sleep study and neuropsychological assessment (0–5 years), body mass index, antidepressant use, and sedative use.

One of the next steps is for the researchers to explore the aspects of sleep health most strongly related to dementia risk.

The study's findings highlight the importance of getting good quality sleep and avoiding sleep apnea for maintaining cognitive function as we age. If you are concerned about your sleep, talk to your doctor.

Journal Information: Matthew P. Pase et al, Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults, JAMA Network Open (2023). DOI: 10.1001/jamanetworkopen.2023.25152